01200nas a2200265   4500000000100000008004100001260001300042653001000055653002600065653001100091653001100102653001200113653000900125653001400134653000900148100001600157700001200173700001600185700001100201245005500212300001100267490000700278520063500285022001400920       1996                            d  c1996 Sep10aAdult10aAnti-Infective Agents10aBiopsy10aHumans10aleprosy10aMale10aOfloxacin10aSkin1 aMochizuki Y1 aOishi M1 aNishiyama C1 aIida T00aActive leprosy treated effectively with ofloxacin.  a749-510 v353 a<p>The patient is a 25-year-old Filipino who showed polymorphous eruptions over the whole body, right ulnar nerve paresis, polyneuropathy and hypalgesia in the area of eruptions. Because the biopsy specimen showed foam cells, histiocytes, epithelioid cells, many Mycobacterium leprae and no giant cells, the diagnosis of borderline-lepromatous (BL) type was made. The symptoms were improved by the administration of 300 mg/day ofloxacin. Because the monotherapy using ofloxacin has been reported to be effective in all 5 previously reported cases of BL type leprosy, it may be recommended for a larger number of leprosy cases.</p>  a0918-2918