01359nas a2200265   4500000000100000008004100001260001300042653001800055653001000073653002800083653001100111653001100122653001200133653000900145653001600154653001900170100001300189700001400202700001600216245004400232300001100276490000700287520078500294022001401079       2000                            d  c2000 May10aAcute disease10aAdult10aDiagnosis, Differential10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aSporotrichosis1 aRamesh V1 aBeena K R1 aMukherjee A00aSporotrichoid presentations in leprosy.  a227-300 v253 a<p>Two adult patients of leprosy, one woman and one man, presented with a clinical picture simulating sporotrichosis. The skin and regional nerve trunk was affected in one, and in the other the disease was confined to the nerve. Both had features of an upgrading reaction following anti-leprosy therapy; this was seen as erosion and scarring of the plaque, and acute onset of abscesses along the easily palpable and thickened nerve that ruptured through the skin. The diagnosis was supported by histopathology. In the light of other infections that give rise to a sporotrichoid pattern of infection it is concluded that leprosy should also be included in this category so that early diagnosis and use of corticosteroids can be implemented quickly to prevent nerve destruction.</p>  a0307-6938