01745nas a2200349 4500000000100000008004100001260001300042653001000055653000900065653001500074653002500089653001100114653002200125653001500147653001100162653001600173653001200189653000900201653001600210653001400226653001200240100001600252700001100268700001500279245009400294856005900388300001000447490000700457050003200464520088500496022001401381 1996 d c1996 Sep10aAdult10aAged10aAmputation10aDeveloping countries10aFemale10aFollow-Up Studies10aFoot Ulcer10aHumans10aHyperplasia10aleprosy10aMale10aMiddle Aged10aPrognosis10aSenegal1 aGrauwin M Y1 aMane I1 aCartel J L00aPseudoepitheliomatous hyperplasia in trophic ulcers in leprosy patients. A 28-case study. uhttp://leprev.ilsl.br/pdfs/1996/v67n3/pdf/v67n3a06.pdf a203-70 v67 aInfolep Library - available3 a
Between 1984 and 1993, pseudoepitheliomatous hyperplasia developing in chronic ulcers were observed in 28 former Senegalese leprosy patients, which amounts to an annual frequency of 1.9 per 1000 ulcers. Correct diagnosis could only be made by histopathological examination of specimens taken from the depth of the lesion. Amputation was carried out on 17 patients and local excision on the other 10. Recurrence of growth was observed in 8 of the 10 patients treated by excision; in all of these 8 cases below knee amputation had to be subsequently performed. From our experience, it may be assumed that local excision should be carried out only in the case of small tumours. Since the aim of surgical procedure is to allow the patient to have physical autonomy, below knee amputation, followed by adaptation of prosthesis, should be the procedure chosen in the other cases.
a0305-7518