01528nas a2200313   4500000000100000008004100001260001700042653001100059653002000070653002400090653001400114653001100128653001200139653002400151653002500175653001600200653002400216653000900240653001800249100001200267700001300279700001200292700001200304245006600316300001100382490000700393520080000400022001401200       1996                            d  c1996 Jul-Aug10aBiopsy10aColoring Agents10aDouble-Blind Method10aGranuloma10aHumans10aleprosy10aLeprosy, Borderline10aLeprosy, lepromatous10aLymphocytes10aProspective Studies10aSkin10aSkin Diseases1 aSingh N1 aBhatia A1 aGupta K1 aRamam M00aCytomorphology of leprosy across the Ridley-Jopling spectrum.  a719-230 v403 a<p><b>OBJECTIVE: </b>To evaluate the possible role of cytology in classifying leprosy lesions on the Ridley-Jopling scale.</p><p><b>STUDY DESIGN: </b>A double-blind, prospective study comparing cytologic assessment of 30 clinically diagnosed cases of leprosy with their histopathology. May-Grünwald-Giemsa and Ziehl-Neelsen stain were done on slit skin smears and fine needle aspiration material.</p><p><b>RESULTS: </b>Cytologic subclassification was possible in 23 cases as tuberculoid leprosy (11), midborderline (3), borderline lepromatous (5) and lepromatous leprosy (4). These correlated with histologic subtypes.</p><p><b>CONCLUSION: </b>May-Grünwald-Giemsa complements Ziehl-Neelsen stain, yielding information almost comparable to that from histologic examination of skin biopsies.</p>  a0001-5547