01704nas a2200385 4500000000100000008004100001260001300042653000900055653002400064653002500088653001100113653001600124653001100140653002100151653002100172653001200193653002400205653000900229653001600238653001700254653001200271100001500283700001200298700001200310700001300322700001100335700001400346700001200360700001200372245003500384300001000419490000700429520086800436022001401304 1995 d c1995 Nov10aAged10aAntigens, Bacterial10aCase-Control Studies10aFemale10aGlycolipids10aHumans10aImmunoglobulin G10aImmunoglobulin M10aleprosy10aLipopolysaccharides10aMale10aMiddle Aged10aRisk Factors10aUveitis1 aNamisato M1 aMorii K1 aAsami S1 aHaraya A1 aJoko S1 aKawatsu K1 aIzumi S1 aOgawa H00a[Uveitis in leprosy patients]. a230-50 v643 a
We examined 24 dermatologically cured leprosy patients with ongoing uveitis (UV+) and 22 age and type matched controls (UV-) to study the late phase leprous UV. All patients have been skin smear negative for more than 10 years. The history of chemotherapy, 5 years before and after a accomplishing bacterial negativity, was evaluated and represented by "SCORE". It was found that anti-PGL-I and anti-LAM-B antibodies were significantly higher in UV+ group compared to the controls. The mean SCORE of chemotherapy in UV+ group was significantly lower than in the controls. Iris pearls were seen in 10 cases or 42% out of 24 UV+ patients. No iris pearls were seen in control group. These results suggest that insufficient chemotherapy and consequent incomplete elimination of bacilli are the risk factors for leprous UV in the quiescent stage of the disease.
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