01464nas a2200277   4500000000100000008004100001260001300042653001000055653001200065653001100077653001100088653001200099653000900111653002300120100001900143700001700162700001100179700001800190700001300208700001600221245006200237300001000299490000700309520085600316022001401172       1993                            d  c1993 Mar10aAdult10aDapsone10aFemale10aHumans10aleprosy10aMale10aPatient Compliance1 aPiscitelli S C1 aDanziger L H1 aHill C1 aSlajchert A A1 aWest D P1 aFischer J H00aEffectiveness of a dapsone compliance program in leprosy.  a206-90 v323 a<p><b>BACKGROUND: </b>Long-term effectiveness of a dapsone compliance program was assessed in patients with leprosy.</p><p><b>METHODS: </b>The monitoring program consists of urine dapsone/creatinine ratio determination at each visit with subsequent patient feedback and education. Eighty-eight patients receiving dapsone and seen in a leprosy clinic from 1985-1990 were included.</p><p><b>RESULTS: </b>The proportion of patients compliant with dapsone during a given year ranged from 70.0% (1987) to 94.4% (1989). Overall compliance for the 6-year period was 81.6%. This level of compliance was significantly different (P < 0.05) than the baseline compliance in the leprosy clinic of 46.7%.</p><p><b>CONCLUSIONS: </b>Compliance monitoring, combined with active patient involvement, was effective in sustaining high compliance over a 6-year period.</p>  a0011-9059