01692nas a2200337   4500000000100000008004100001260001300042653001000055653000900065653000800074653003000082653001100112653001100123653001200134653002500146653000900171653001600180100001300196700001200209700001300221700000900234700000900243700001000252245010200262856005900364300001000423490000700433050003200440520086800472022001401340       1993                            d  c1993 Mar10aAdult10aAged10aEye10aEye Infections, Bacterial10aFemale10aHumans10aleprosy10aLeprosy, Tuberculoid10aMale10aMiddle Aged1 aBrandt F1 aShi Z R1 aZhou H M1 aLu B1 aWu H1 aRai N00aA histological study of the eye lesions in 12 leprosy patients with tuberculoid lesion in 4 eyes.  uhttp://leprev.ilsl.br/pdfs/1993/v64n1/pdf/v64n1a06.pdf  a44-520 v64  aInfolep Library - available3 a<p>The histological reactions in 12 eyes of 12 leprosy patients were studied (5 BT, 1 BB, 1 BL and 5 LL). Granuloma lesions composed of epithelioid cells, Langerhans giant cells, macrophages and lymphocytes were found in various intraocular tissues, e.g. cornea, sclera, iris, ciliary body or retina in 4 patients (1 BT and 3 LL). Of the 3 LL patients, according to the records, 2 were cured and in the other patient the outcome of the treatment was not mentioned. In view of the finding of the granulomatous lesions in the clinically cured patients and tuberculoid granuloma in the intraocular tissues in the LL patients, could there be some peculiarities in the intraocular sites? Or perhaps the tuberculoid reaction is just a manifestation of an upgrading reaction? More examinations on human leprosy eye specimens will be needed to answer these questions.</p>  a0305-7518