00961nas a2200229 4500000000100000008004100001260001300042653001900055653001000074653001600084653001100100653001200111653001600123653000900139100001400148700001100162245005300173300000900226490000700235520047500242022001400717 1993 d c1993 Jan10aAbdominal pain10aAdult10aClofazimine10aHumans10aleprosy10aLymph Nodes10aMale1 aChong P Y1 aTi T K00aSevere abdominal pain in low dosage clofazimine. a24-60 v253 a
We describe a 41 yr old leprosy patient treated for 10 yrs with clofazimine who underwent laparotomy for severe abdominal pain. At surgery, the only significant findings were that the coeliac lymph nodes were enlarged and stained purplish black as were the omentum and the intraperitoneal fat. No other cause of abdominal pain was identified. On histological examination, reddish-purple crystals were identified at frozen section but not in the paraffin sections.
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