01711nas a2200337 4500000000100000008004100001260001300042653001000055653001100065653001100076653002800087653002700115653001200142653002400154653002500178653000900203653001600212653003200228100001700260700001600277700001300293700001300306700001700319700001500336245004700351856004100398300001000439490000700449520090300456022001401359 1993 d c1993 Mar10aAdult10aFemale10aHumans10aKidney Failure, Chronic10aKidney Transplantation10aleprosy10aLeprosy, Borderline10aLeprosy, lepromatous10aMale10aMiddle Aged10aPostoperative Complications1 aRoselino A M1 aAlmeida A M1 aFoss N T1 aLima V J1 aRaspanti E O1 aFerraz A S00aRenal transplantation in leprosy patients. uhttp://ila.ilsl.br/pdfs/v61n1a15.pdf a102-50 v613 a
We report four cases of leprosy in renal transplant recipients, two of whom had the disease before transplantation and no signs of relapse even in the presence of immunosuppressive drugs. The other two cases presented with lepromatous and borderline (dimorphous) leprosy 5 months and 5 years after transplantation, respectively. The disease of the last patient was controlled with sulfone even in the presence of immunosuppressive drugs, but the mechanism whereby the first patient rapidly developed lepromatous leprosy is unclear, even though he was a home contact of a patient with lepromatous leprosy (his wife). In view of the data presented here, we do not contraindicate renal transplantation in patients with leprosy who frequently suffer changes in renal function. We believe that renal function should be periodically evaluated in patients with borderline and lepromatous leprosy.
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