01319nas a2200301   4500000000100000008004100001260001300042653001500055653001000070653001600080653002500096653001100121653001100132653001200143653001100155653000900166653001500175100001400190700002300204700001400227245007600241856008600317300000900403490000800412050001400420520056900434022001401003       1993                            d  c1993 Aug10aAdolescent10aAdult10aBCG Vaccine10aCase-Control Studies10aFemale10aHumans10aleprosy10aMalawi10aMale10aOdds Ratio1 aBaker D M1 aNguyen-Van-Tam J S1 aSmith S J00aProtective efficacy of BCG vaccine against leprosy in southern Malaŵi.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271193/pdf/epidinfect00040-0030.pdf  a21-50 v111  aBAKER19933 a<p>This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malaŵi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44.8%, compared to 62.5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63.6%; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.</p>  a0950-2688