01386nas a2200361 4500000000100000008004100001260000900042653001500051653001000066653000900076653001600085653002500101653001500126653001000141653001500151653001100166653001400177653001100191653002000202653001200222653000900234653001600243100001800259700001600277700001400293700001200307700001600319245003600335300001000371490000700381520062200388022001401010 1993 d c199310aAdolescent10aAdult10aAged10aAlbuminuria10aBeta 2-Microglobulin10aBiomarkers10aChild10aCreatinine10aFemale10aHematuria10aHumans10aKidney Diseases10aleprosy10aMale10aMiddle Aged1 aKirsztajn G M1 aNishida S K1 aSILVA M S1 aAjzen H1 aPereira A B00aRenal abnormalities in leprosy. a381-40 v653 a
We have evaluated laboratory and clinical manifestations of renal disease in 96 patients with leprosy, looking for a sensitive and early marker for detection and possibly follow-up of nephropathy in these patients. Microscopic hematuria was observed in 21.9% of the cases (with dysmorphic erythrocytes in 71.4% of them). Abnormal microalbuminuria and urinary beta 2-microglobulin were found in 15.8 and 19.8% of the cases, respectively. We have observed a high frequency of hematuria, abnormal microalbuminuria and elevation of urinary beta 2-microglobulin in these patients still with normal serum creatinine.
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