01293nas a2200265   4500000000100000008004100001260001300042653001900055653001100074653001200085653002500097653001700122653003000139100001500169700001100184700001200195700001500207700001100222245012600233856004100359300001100400490000700411520059500418022001401013       1993                            d  c1993 Sep10aDNA, Bacterial10aHumans10aleprosy10aMycobacterium leprae10aNasal Mucosa10apolymerase chain reaction1 aPattyn S R1 aUrsi D1 aIeven M1 aGrillone S1 aRaes V00aDetection of Mycobacterium leprae by the polymerase chain reaction in nasal swabs of leprosy patients and their contacts.  uhttp://ila.ilsl.br/pdfs/v61n3a02.pdf  a389-930 v613 a<p>Nose swabs from 4 paucibacillary (PB) and 8 multibacillary (MB) leprosy patients and their contacts were tested for the presence of Mycobacterium leprae by two polymerase chain reactions (PCR); 30% of the samples contained inhibitors for the PCR, 1 of 52 (1.9%) swabs and 13 of 164 (7.9%) swabs were positive for M. leprae among contacts of PB and MB patients, respectively. Since this difference is not significant, and some positives were found among contacts of MB patients treated and cured of their infection, it is concluded that the observed infections are community acquired.</p>  a0148-916X