01434nas a2200289   4500000000100000008004100001260001300042653001000055653002600065653003000091653001600121653002800137653001100165653001100176653000900187653002600196653001800222653001800240100001400258700001400272700001300286245008300299300001100382490000700393520073000400022001401130       1993                            d  c1993 Dec10aAdult10aAnti-Bacterial Agents10aCombined Modality Therapy10aDebridement10aDiagnosis, Differential10aFemale10aHumans10aMale10aRetrospective Studies10aRhinoscleroma10aUnited States1 aAndraca R1 aEdson R S1 aKern E B00aRhinoscleroma: a growing concern in the United States? Mayo Clinic experience.  a1151-70 v683 a<p>Rhinoscleroma is a chronic, progressive, granulomatous infection of the upper airways caused by the bacterium Klebsiella rhinoscleromatis. Although most cases occur in developing countries, recent immigration patterns have led to an increasing number of patients with rhinoscleroma in the United States. Rhinoscleroma may mimic various inflammatory and neoplastic processes, including leprosy, paracoccidioidomycosis, sarcoidosis, basal cell carcinoma, and Wegener's granulomatosis. Current therapy consists of a combination of surgical débridement and prolonged antimicrobial therapy. Rhinoscleroma should be added to the list of opportunistic infections that can occur in patients with human immunodeficiency virus.</p>  a0025-6196