01583nas a2200349   4500000000100000008004100001260001300042653001000055653001900065653001300084653002200097653001200119653001100131653001900142653001300161653001100174653001900185653002500204653000900229653001600238653001500254653002100269653002800290100001600318700001600334245010700350856004100457300001000498490000700508520070400515022001401219       1994                            d  c1994 Jun10aAdult10aAutoantibodies10aCollagen10aConnective Tissue10aElastin10aFemale10aGrowth Hormone10aHormones10aHumans10aHydrocortisone10aLeprosy, lepromatous10aMale10aMiddle Aged10aThyronines10aTriiodothyronine10aTuberculosis, Pulmonary1 aBalybin E S1 aVinnick L A00aAutosensitization to connective tissue elements and endogenous adaptation hormones in mycobacterioses.  uhttp://ila.ilsl.br/pdfs/v62n2a04.pdf  a225-80 v623 a<p>The contribution of some adaptation hormones to the process regulating production of autoantibodies to collagen (Abc) and elastin (Abe) was studied in leprosy (37 patients) and tuberculosis (31 patients). In both mycobacterioses the Abc and Abe titers were increased and inversely correlated with endogenous cortisol levels. In leprosy the antibody titers directly correlated with the triiodothyronine (T3) levels which were significantly higher than the values in healthy controls. A new approach to research for remedies and methods of preventing and curing autosensitization to connective tissue is suggested by combining medications according to individual endocrine and immune indices.</p>
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