01403nas a2200229   4500000000100000008004100001260001700042653003200059653003100091653002200122653001200144100001400156700002000170700001600190700001800206245019100224300000900415490000700424050003200431520069600463022001401159       1994                            d  c1994 Jan-Mar10aMicrobial Sensitivity Tests10aMycobacterium tuberculosis10aPlants, Medicinal10aPowders1 aHerbert D1 aParamasivan C N1 aPrabhakar R1 aSwaminathan G00aIn vitro experiments with Centella asiatica: investigation to elucidate the effect of an indigenously prepared powder of this plant on the acid-fastness and viability of M. tuberculosis.  a65-80 v66  aInfolep Library - available3 a<p>The herb Centella asiatica (Linn.), found throughout India, is acclaimed to have medicinal properties and has been used in leprosy patients from very early times. It is considered that the active compound of this herb, called asiaticoside, probably acts on the waxy covering of M. leprae. The in vitro effect of an indigenously produced dry powder of Centella asiatica (CA) on the acid-fastness and viability of M. tuberculosis was investigated in the present study. The results indicate that CA may not have any direct action on the acid-fastness or viability of M.tuberculosis H37Rv in vitro. Further studies using purified asiaticoside of the plant or in vivo studies are required.</p>  a0254-9395