01697nas a2200313 4500000000100000008004100001260001300042653001000055653001600065653002500081653002500106653001100131653001100142653001100153653001200164653000900176653001600185653001800201653001600219100001300235700001200248700001200260245008900272856004100361300001000402490000700412520095000419022001401369 1994 d c1994 Sep10aAdult10aAge Factors10aAnalysis of Variance10aCase-Control Studies10aCornea10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aMyelin Sheath10aSex Factors1 aDaniel E1 aDavid A1 aRao P S00aQuantitative assessment of the visibility of unmyelinated corneal nerves in leprosy. uhttp://ila.ilsl.br/pdfs/v62n3a05.pdf a374-90 v623 a

Unmyelinated corneal nerves were counted in 383 leprosy patients whose eyes looked normal on clinical examination and in an equal number of healthy controls. Visibility of these nerves was decreased significantly (p < 0.01) in the nasal half of the cornea in both patients and controls. There was a significant (p < 0.01) inverse correlation between age and the visibility of these nerves in patients and controls. There was a significant (p < 0.05) reduction in the visibility of these nerves as the spectrum of the disease moved from the tuberculoid to the lepromatous pole. There was no significant correlation between visibility of these nerves and the smear positivity of the patient. Neither did duration of the disease nor the duration of antileprosy treatment alter the visibility of these nerves significantly. Overall, there was a reduction in the visibility of these nerves in patients who had had leprosy reactions.

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