01195nas a2200325 4500000000100000008004100001260001300042653001200055653001800067653000900085653001400094653001200108653001000120653000900130653000900139653001500148653000900163653000900172653001100181653000900192100001200201700001400213700001700227245006300244856004100307300001000348490000700358520049000365022001400855 1994 d c1994 Sep10aAnimals10aEar, External10aFoot10aGranuloma10aleprosy10aLiver10aLung10aMice10aMice, Nude10aNose10aSkin10aSpleen10aTail1 aJob C K1 aChehl S K1 aHastings R C00aTransmission of leprosy in nude mice through thorn pricks. uhttp://ila.ilsl.br/pdfs/v62n3a08.pdf a395-80 v623 a

The dorsum of the feet of 10 nude mice was smeared with 10(7) Mycobacterium leprae and then pricked with cactus thorns contaminated with M. leprae. In 15 months five of them developed lepromatous nodules at the infected site and disseminated lesions in the ears, nose, tail and the organs of the reticuloendothelial system. Penetrating injuries through unprotected skin contaminated with M. leprae from the environment may play a role in the transmission of leprosy in humans.

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