01489nas a2200301   4500000000100000008004100001260001300042653002000055653001900075653003400094653002000128653001100148653002600159653002100185653002100206653001200227653001800239653002000257100001200277700001100289700001500300245005900315300001000374490000700384050003200391520075000423022001401173       1978                            d  c1978 Apr10aAlpha-Globulins10aBeta-Globulins10aBlood Protein Electrophoresis10aGamma-Globulins10aHumans10aImmunoelectrophoresis10aImmunoglobulin G10aImmunoglobulin M10aleprosy10aSerum Albumin10aSerum Globulins1 aSaoji A1 aMene A1 aSHARMA K D00aElectrophoresis and immuno electrophoresis in leprosy.  a161-50 v50  aInfolep Library - available3 a<p>50 cases of leprosy belonging to various subgroups i.e. 10 tuberculoid, 25 lepromatous leprosy, 10 lepra reaction, 5 dimorphic leprosy, and 25 cases or normal individuals were subjected to agar gel electrophoresis. The slides were scanned by densitometry. It showed profound departure from normal in various fractions of electrophoretic patterns. All of them showed rise of gamma globulin. Albumin was markedly decreased in lepromotous leprosy and lepra reaction. In dimorphic leprosy Alfa-1 was decreased. Qualitative immuno electrophoresis was done by using antihuman serum raised in the laboratory, by immunising rabbits. It revealed changes in IgM and IgG arcs. Results are discussed and tried to explain on immunological derangement.</p>  a0024-1024