01442nas a2200325 4500000000100000008004100001260001300042653001500055653001000070653002600080653003100106653002000137653003200157653001100189653001100200653001200211653000900223653001600232653002500248100001400273700001600287700001600303700001400319700001300333245012400346300001100470490000700481520061400488022001401102 1994 d c1994 Jul10aAdolescent10aAdult10aAntibodies, Bacterial10aAntigen-Antibody Reactions10aContact Tracing10aEvaluation Studies as Topic10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aMycobacterium leprae1 aSingh N B1 aBhatnagar S1 aChoudhary A1 aGupta H P1 aKaul S M00aEvaluation of diversified antigens for detection of Mycobacterium leprae antibodies from leprosy patients and contacts. a478-810 v323 a

A comparative evaluation of diversified antigens in ELISA has been made for detection of M. leprae antibodies in the sera of leprosy patients and their contacts. Out of the four antigens, namely M. leprae sonicate (ML), phenolic glycolipid I (PGL-1), M. habana sonicate (MH) and its arabinomannan (AM), the cross reactive antigens (MH,AM) have comparatively detected more number of leprosy cases. Homologous antigens (ML, PGL-1) have lower detection level. Use of MH and AM for detection of mycobacterial antibodies have been discussed and advocated for epidemiological studies of leprosy/tuberculosis.

 a0019-5189