01194nas a2200217 4500000000100000008004100001260000900042653001800051653003500069653001100104653002000115653001200135100001400147700001400161700001600175245004500191300001100236490000700247520070800254022001400962 1976 d c197610aB-Lymphocytes10aFluorescent Antibody Technique10aHumans10aImmunoglobulins10aleprosy1 aFaber W R1 aLeiker DL1 aCormane R H00aImmunoglobulin-bearing cells in leprosy. a319-260 v563 a
Peripheral blood lymphocytes of 28 untreated and 17 treated patients with different types of leprosy were investigated for the occurrence of immunoglobulin (Ig) bearing cells by means of a smear method. Seven healthy Africans served as controls. In a later stage a complementary study was performed on 6 tuberculoid and 6 lepromatous leprosy patients by means of a suspension method. The immunofluorescence technique was used for the detection of Ig-bearing cells, In tuberculoid leprosy an increase of Ig-bearing cells seems to occur during treatment, predominantly expressed by an increase in IgD-bearing cells. In lepromatous leprosy no increased percentages of Ig-bearing cells were observed.
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