01431nas a2200325   4500000000100000008004100001260001300042653001000055653002400065653001000089653003700099653001100136653001600147653001100163653001200174653000900186653001000195653002000205100001500225700001400240700001400254700001300268245013200281856005900413300001000472490000700482050003200489520057000521022001401091       1994                            d  c1994 Dec10aAdult10aAntigens, Bacterial10aChild10aDisease Transmission, Infectious10aFemale10aGlycolipids10aHumans10aleprosy10aMale10aNepal10aSerologic Tests1 aSoares D J1 aFailbus S1 aChalise Y1 aKathet B00aThe role of IgM antiphenolic glycolipid-1 antibodies in assessing household contacts of leprosy patients in a low endemic area.  uhttp://leprev.ilsl.br/pdfs/1994/v65n4/pdf/v65n4a03.pdf  a300-40 v65  aInfolep Library - available3 a<p>This study was carried out to assess the role PGL-1 antibodies may have to play in assisting with early diagnosis in close contacts of leprosy patients. Blood samples were collected from patients and contacts. It was found that 6.9% of index cases and 1% of healthy contacts were positive for PGL-1 antibody. None of the healthy contacts developed clinical leprosy and all had become seronegative at follow-up. We conclude that screening for PGL-1 antibodies has a limited role in the screening of healthy contacts and may not be of use in low endemic areas.</p>  a0305-7518