01222nas a2200277 4500000000100000008004100001260001700042653001200059653000900071653002300080653001200103653001600115653000900131653001400140653002900154653002500183100001900208700001400227700001100241245013600252856004300388300001100431490000700442520048100449022001400930 1976 d c1976 Jan-Jun10aAnimals10aFoot10aImmunity, Cellular10aleprosy10aMacrophages10aMice10aMonocytes10aMycobacterium Infections10aMycobacterium leprae1 aKrahenbuhl J L1 aWelch T M1 aLevy L00aThe presence of systemic and local activated macrophages in mice infected in the foot pad with Mycobacterium leprae and M. marinum. uhttp://ila.ilsl.br/pdfs/v44n1-2a40.pdf a206-150 v443 a
A highly sensitive assay for quantitating the presence of activated macrophages was employed to show that foot pad infection of mice with neither M. leprae nor M. marinum induced a population of activated peritoneal macrophages. In vitro attempts to demonstrate local activated macrophages in the foot pads of M. leprae infected mice failed, but, because of the technical problems encountered, do not preclude their presence. Additional studies are being carried out.
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