01148nas a2200253 4500000000100000008004100001260000900042653001200051653002400063653002300087653001600110653001200126653000900138653000900147653002100156653001800177653002500195100001400220700001800234245006400252300000900316520055500325022001400880 1995 d c199510aAnimals10aAntigens, Bacterial10aBacterial Vaccines10aBCG Vaccine10aleprosy10aMale10aMice10aMice, Inbred CBA10aMycobacterium10aMycobacterium leprae1 aIushin IM1 aKalianina O V00a[Protective properties of M. lufu in experimental leprosy]. a47-83 a

A protective potential of M. lufu against experimental lepra was studied in mice infected with M. leprae according to Shepard. 5 and 9 months after the inoculation quantitation of the causative agent in the animals' paws indicated a protective action of M. lufu which exceeded that of BCG, M. vaccae and M. leprae. High protective activity of M. lufu is due both to its antigenic composition similarity with M. leprae and influence on immune response regulation. It is suggested to use M. lufu for design of highly effective antilepra vaccine.

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