01226nas a2200229 4500000000100000008004100001260001300042653001200055653002200067653001800089653001300107653001000120100001600130700001800146700002000164700001700184245008900201300001000290490000700300520067500307022001400982 1995 d c1995 Feb10aAnimals10aDisease Outbreaks10aFish Diseases10aSyndrome10aUlcer1 aMukherjee M1 aChakrabarti A1 aChakrabarty A N1 aDastidar S G00aA pathogenicity model for the agents of epizootic ulcerative syndrome (EUS) in fish. a134-50 v333 a

Chemoautotrophic nocardioform (CAN) bacteria had been repeatedly isolated from fish with ulcerative disease syndromes (EUS) from the massive epizootics that had repeatedly occurred since 1988 in eastern India as the major or only pathogenic agent in the background of distinctive environmental and epizootic data. Since these isolates bear significant similarity to the human and rat leprosy bacilli, attempts had been made to demonstrate the pathogenicity of this fish pathogen in the "Swiss" strain of mice as a convenient model. The studies reveal that the fish CAN bacteria could produce pathogenic effects in mice similar to that of the rat leprosy bacillus.

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