01287nas a2200289   4500000000100000008004100001260001300042653001900055653001200074653001100086653002200097653002500119653001100144653001200155653000900167653001600176653001500192100001400207700001600221700001700237245013600254856004100390300001000431490000700441520053500448022001400983       1995                            d  c1995 Mar10aBone and Bones10aEngland10aFemale10aHistory, Medieval10aHospitals, Religious10aHumans10aleprosy10aMale10aPeriostitis10aPrevalence1 aLewis M E1 aRoberts C A1 aManchester K00aInflammatory bone changes in leprous skeletons from the medieval Hospital of St. James and St. Mary Magdalene, Chichester, England.  uhttp://ila.ilsl.br/pdfs/v63n1a11.pdf  a77-850 v633 a<p>The extent and location of an inflammatory bone lesion, periostitis, were examined in 50 leprous skeletons from the Chichester cemetery of the Hospital of St. James and St. Mary Magdalene in Sussex, England. Although the presence of periostitis is not pathognomonic of leprosy, it predominantly indicates dermal and neuropathic changes that the patient would have presented in life. The spread of inflammation across the knee joint and the ossification of the interosseous membrane due to inflammation are also suggested.</p>
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