01191nas a2200301   4500000000100000008004100001260001300042653001000055653000900065653001300074653001700087653001100104653001000115653001200125653001600137653001600153653001400169653001700183100001300200700001100213700001200224700001600236245008400252300000900336490000700345520052300352022001400875       1978                            d  c1978 Jan10aAdult10aAged10aEpitopes10aHLA Antigens10aHumans10aJapan10aleprosy10aLymphocytes10aMiddle Aged10aPhenotype10aTuberculosis1 aTakata H1 aSada M1 aOzawa S1 aSekiguchi S00aHLA and mycobacterial infection: increased frequency of B8 in Japanese leprosy.  a61-40 v113 a<p>A total of 60 leprosy patients, 28 of lepromatous and 32 of tuberculoid form, and 70 active tuberculosis patients was compared with a control of 184 for 34 HLA specificities. The most interesting finding was an increased frequency (10.0%) for HLA-B8 (corrected P = 0.062, relative risk = 20.3) in the leprosy patients as compared with the control group, despite the fact that the frequency of HLA-B8 was extremely low in Japanese. Furthermore, all leprosy patients with B8 had leprous member(s) in their family.</p>  a0001-2815