01167nas a2200229   4500000000100000008004100001260001700042653002400059653002300083653001100106653002800117653001200145653001800157100001500175700001500190700001400205245005900219300000900278490000700287520062900294022001400923       1995                            d  c1995 Jan-Feb10aAntigens, Bacterial10aHistocytochemistry10aHumans10aImmunoenzyme Techniques10aleprosy10aMycobacterium1 aPagliari C1 aDuarte M I1 aSotto M N00aPattern of mycobacterial antigen detection in leprosy.  a7-120 v373 a<p>Immunohistochemistry reaction (Peroxidase anti-peroxidase--PAP) was carried out on fifty-two skin biopsies from leprosy patients with the purpose to identify the antigenic pattern in mycobacteria and to study the sensitivity of this method. Five different patterns were found: bacillar, granular, vesicular, cytoplasmatic and deposits, classified according to the antigenic material characteristics. Deposits (thinely particulate material) appeared more frequently, confirming the immunohistochemistry sensitivity to detect small amounts of antigens even when this material is not detected by histochemical stainings.</p>  a0036-4665