01398nas a2200253   4500000000100000008004100001260001300042653002100055653003000076653001700106653001500123653001100138653001100149653001200160653002100172653001300193100001600206700001200222245006200234300001100296490000700307520081600314022001401130       1995                            d  c1995 Jun10aCell Aggregation10aErythrocyte Deformability10aErythrocytes10aHematocrit10aHumans10aLasers10aleprosy10aReference Values10aRheology1 aKumaravel M1 aSingh M00aAggregation and deformability of erythrocytes in leprosy.  a408-150 v333 a<p>The hemorheological parameters, erythrocyte aggregation and deformability are determined in leprotic patients and are compared with that of healthy subjects. The aggregation is determined by sequential analysis of the He-Ne laser transmission data through erythrocyte suspension at hematocrit 5%. The erythrocyte deformability is determined by measurement of passage time (reciprocal of deformability) of erythrocyte suspension in PBS at hematocrit 6% through cellulose membrane. The observations show that in leprosy the aggregation of erythrocyte is marginally reduced and the deformability is significantly increased. These parameters in combination with low hemoglobin and hematocrit levels in these patients lowers the blood viscosity to maintain the transport of material across the capillary wall.</p>  a0019-5189