01410nas a2200301   4500000000100000008004100001260001300042653001000055653000900065653003000074653001100104653001400115653001100129653002300140653002500163653000900188653001600197653000900213653001700222100001400239700001600253245007900269856004100348300001100389490000700400520068700407022001401094       1995                            d  c1995 Sep10aAdult10aAged10aDrug Therapy, Combination10aFemale10aGranuloma10aHumans10aLeprostatic Agents10aLeprosy, lepromatous10aMale10aMiddle Aged10aSkin10aTime Factors1 aDesikan P1 aDesikan K V00aPersistence of lepromatous granuloma in clinically cured cases of leprosy.  uhttp://ila.ilsl.br/pdfs/v63n3a06.pdf  a417-210 v633 a<p>Multibacillary (MB) leprosy patients are declared cured when they become bacteriologically negative and their lesions do not show any signs of clinical activity. Whether there is also a corresponding histological clearance of skin lesions is not known. The present study was carried out on the histopathology of the skin of 40 MB cases who were declared cured with multidrug (MDT). In 22 of them, small lepromatous granulomas were seen to persist, although acidfast bacilli were not found in them. The presence of these granulomas was not found to have any significant associated with the duration of the disease, length of treatment, or the period of cessation of therapy.</p>
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