01880nas a2200361   4500000000100000008004100001260001300042653001500055653001000070653000900080653002200089653001000111653001000121653001200131653003000143653001100173653001100184653001400195653002300209653001200232653000900244653001600253653001500269653001300284100000900297700001100306700000900317245012100326300001700447490000700464520103300471022001401504       1995                            d  c1995 Jun10aAdolescent10aAdult10aAged10aAged, 80 and over10aChild10aChina10aDapsone10aDrug Therapy, Combination10aFemale10aHumans10aIncidence10aLeprostatic Agents10aleprosy10aMale10aMiddle Aged10aPrevalence10aRifampin1 aLi H1 aWeng X1 aLi T00a[Long-term effect of leprosy control in both highly endemic prefectures, Weifang of Shandong and Wenshan of Yunnan].  a333-7, 381-20 v753 a<p>The long-term effect of leprosy control was studied in two prefectures of different geographical conditions and socio-economic status. During 1955-1985, the incidence rate in Weifang of Shandong decreased by 94.5% (9.1-0.5/10,000) and became evident after the introduction of MDT in 1986 (0.04/10,000, 1993). In Wenshan of Yunnan, however, it remained at about 20/10,000 before 1980. After the introduction of rifampin plus dapsone in 1979 and fixed duration MDT in 1986, it decreased by 94% (20-1.2/10,000), whereas the detection rate remained constant (+5/100,000). In comparison with the features of new patients detected since 1980, we noted a steady increase of MB rate and voluntary reporting, and a decrease of deformity rate, in the last 8 years in Weifang. It is estimated that by the year 2000 Weifang may have the detection rate of 0.001260/10 thousand and the incidence rate of 0/00757/10 thousand in contrast to the detection rate of 0.2980/10 thousand and the incidence rate of 0.316/10 thousand in Wenshan.</p>  a0376-2491