01332nas a2200277   4500000000100000008004100001260000900042653001000051653002600061653001600087653001200103653003000115653002000145653001100165653001200176653000900188100001400197700001500211700001300226700001600239245006400255300001000319490000700329520070400336022001401040       1978                            d  c197810aAdult10aAntineoplastic Agents10aCholestasis10aDapsone10aDrug Therapy, Combination10aHodgkin Disease10aHumans10aleprosy10aMale1 aWeshler Z1 aLeviatan A1 aGordon R1 aKopolovic J00aDevelopment of Hodgkin's disease in a patient with leprosy.  a281-40 v353 a<p>We present a patient with leprosy who developed Hodgkin's disease of the nodular sclerosing type. There are two previous reports describing the combination of leprosy and Hodgkin's disease in a single patient [3, 9]. Hodgkin's disease was diagnosed 14 months after the complete disappearance of mycobacterium leprae from the skin lesions, under treatment with DDS (diamino-diphenyl-sulfone). Hodgkin's disease was treated by irradiation and chemotherapy. Obstructive jaundice developed which resolved under treatment by irradiation of the hilar area of the liver, chemotherapy and hormones. During two years of immuno-suppressive therapy, without DDS, no exacerbation of the leprosy occurred.</p>  a0030-2414