01623nas a2200373   4500000000100000008004100001260001300042653001500055653001000070653001000080653001100090653001200101653001100113653001200124653000900136653001600145653002300161653001700184653002200201653001700223653001800240653000900258653001700267100001500284700001400299700001400313700001400327245013900341300000900480490000700489050003200496520070700528022001401235       1980                            d  c1980 Jan10aAdolescent10aAdult10aChild10aFemale10aFingers10aHumans10aleprosy10aMale10aMiddle Aged10aNerve Degeneration10aNerve Fibers10aNeural Conduction10aRadial Nerve10aSchwann Cells10aSkin10aTime Factors1 aShetty V P1 aMehta L N1 aIrani P F1 aAntia N H00aStudy of the evolution of nerve damage in leprosy. Part I--Lesions of the index branch of the radial cutaneous nerve in early leprosy.  a5-180 v52  aInfolep Library - available3 a<p>A total of six index finger branch of the radial cutaneous (IRC) nerves from three BL, two BB and one BT cases of leprosy, with less than 6 months history of disease were subjected for nerve conduction velocity (NCV) studies followed by biopsy. The biopsy was divided into three parts and subjected for light microscopy quantitative histology, electron-microscopy and fibre tease studies. The nerves revealed a slight reduction in NCV and a varying degree of segmental demyelination ranging from 10% to 35%. The earliest changes observed were the thickening and proliferation of Schwann cell processes of the unmyelinated fibres and degeneration of their axons regardless of the type of leprosy.</p>  a0024-1024