01113nas a2200253 4500000000100000008004100001260001300042653000900055653002900064653001100093653001800104653001100122653001200133653001900145653001000164100001300174700001700187700001600204245008700220300001100307490000600318520052100324022001400845 1980 d c1980 Aug10aAged10aCarcinoma, Squamous Cell10aFemale10aFoot Diseases10aHumans10aleprosy10aSkin Neoplasms10aUlcer1 aTroy J L1 aGrossman M E1 aWalther R R00aSquamous-cell carcinoma arising in a leprous neurotrophic ulcer: report of a case. a659-610 v63 a
Exophytic neoplasms arise rarely in neurotrophic ulcers of leprosy. When such a lesion does develop, it has clinical resemblance to an indolent and locally invasive epithelioma cuniculatum, may invade deeply, and may metastasize. The case described showed deep invasion and extensive involvement of bone. Exophytic neoplasms in neurotrophic ulcers of leprosy should be considered to be squamous-cell carcinomas, not epitheliomata cuniculata, because of their potential for rapid, deep invasion and metastases.
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