01295nas a2200313 4500000000100000008004100001260001700042653001200059653001600071653001200087653002400099653002400123653002000147653001100167653001100178653001200189653002000201653000900221653001800230653001200248653002800260100001900288700001500307245012200322300001000444490000600454520050700460022001400967 1980 d c1980 Sep-Oct10aAmyloid10aAmyloidosis10aAnimals10aArthritis, Juvenile10aBlood Sedimentation10aChronic Disease10aFemale10aHumans10aleprosy10aLeukocyte Count10aMale10aOsteomyelitis10aRabbits10aSerum Amyloid A Protein1 aScheinberg M A1 aBenson M D00aSAA amyloid protein levels in amyloid-prone chronic inflammatory disorders. Lack of association with amyloid disease. a724-60 v73 a
Serum amyloid protein A (SAA) levels were evaluated by a sensitive radioimmunoassay technique in leprosy, juvenile rheumatoid arthritis and chronic osteomyelitis. SAA was elevated in all 3 groups of patients. The level in each of the patient groups did not reflect the presence of secondary amyloidosis. Our study suggests that serum SAA protein levels should not be considered a routine diagnostic test in patients with chronic inflammatory diseases prone to the development of amyloid disease.
a0315-162X