01599nas a2200337   4500000000100000008004100001260001600042653002500058653002500083653003200108653002500140653001400165653001400179653001100193653001600204653001700220100001500237700001400252700001300266700001300279700002500292700001400317700001300331700002200344700001500366245008200381300001100463490000600474520076700480022001401247       1978                            d  c1978 Oct 2810aAlanine Transaminase10aAlkaline Phosphatase10aAspartate Aminotransferases10aBacterial Infections10aGranuloma10aHepatitis10aHumans10aSarcoidosis10aTuberculosis1 aVilaseca J1 aGuardia J1 aCuxart A1 aClotet V1 aMartinez-Vasquec J M1 aBernado L1 aMasana L1 aGarcía-Vanrell G1 aBacardí R00a[Granulomatous hepatitis: aetiological study of 107 cases (author's transl)].  a3323-50 v73 a<p>In this series, the commonest aetiology was tuberculosis (30 cases, 28%), followed by sarcoidosis (18 cases, 17,7%), mediterranean fever (Olmer's disease) (13 cases, 12,1%), brucellosis (8 cases, 7,4%), typhoid fever (7 cases, 6,6%) and idiopathic forms (8 cases, 7,4%). These were followed by Hodgkin's disease, toxoplasmosis, adenosarcoma, and leprosy. Finally, there were single cases due to infectious mononucleosis, B.C.G. reaction, hypogammaglobulinaemia, coeliac disease and temporal arteritis. Half of the patients had hepatomegaly and an increase, in general moderate, in hepatic enzymes (transaminases, alkaline phosphatase). The highest enzyme levels were seen in cases of brucellosis, hepatic enzymes being normal in patients with sarcoidosis.</p>  a0301-1518