01655nas a2200313 4500000000100000008004100001260001300042653002500055653002500080653003200105653001400137653001900151653001100170653001100181653001200192653001000204653002500214653000900239653001800248653002000266100001300286700001500299700001700314245006900331300001100400490000600411520091000417022001401327 1980 d c1980 Dec10aAlanine Transaminase10aAlkaline Phosphatase10aAspartate Aminotransferases10aBilirubin10aBlood Proteins10aFemale10aHumans10aleprosy10aLiver10aLiver Function Tests10aMale10aSerum Albumin10aSerum Globulins1 aPacĂ­n A1 aFliess E L1 aLlorente B E00a[Hepatic function in the clinical spectrum of Hansen's disease]. a93-1110 v53 a

The liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients), reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed.

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