00993nas a2200253   4500000000100000008004100001260001300042653001200055653001200067653003100079653003000110653001100140653001200151653000900163653001300172100001600185700001600201245008300217300001000300490000700310050003200317520037600349022001400725       1981                            d  c1981 Jul10aAnimals10aDapsone10aDrug Resistance, Microbial10aDrug Therapy, Combination10aHumans10aleprosy10aMice10aRifampin1 aGirdhar B K1 aDesikan K V00aPersister M. leprae after introductory rifampicin followed by dapsone therapy.  a350-30 v53  aInfolep Library - available3 a<p>Lepromatous patients of "Introductory Rifampicin therapy' (Lepr. India, 50: 1978) who received 300 mg Rifampicin daily for 3 months followed by 50-100 mg DDS daily for another 21 months are investigated for persisters in the skin. Mouse foot pad results revealed that at the end of 2 years of treatment viable M. leprae are still persisting in 3 out of 6 patients.</p>  a0024-1024