01276nas a2200265 4500000000100000008004100001260001300042653001000055653003100065653001100096653002000107653001200127653000900139653001600148100001600164700001700180700001800197700001600215245005300231300001100284490000700295050003200302520066200334022001400996 1981 d c1981 Jul10aAdult10aGlomerular Filtration Rate10aHumans10aKidney Diseases10aleprosy10aMale10aMiddle Aged1 aSritharan V1 aVenkatesan K1 aBharadwaj V P1 aGirdhar B K00aRenal functions in lepromatous leprosy patients. a437-420 v53 aInfolep Library - available3 a
While leprosy does not primarily affect the kidneys, secondary involvement of kidneys has been reported in lepromatous leprosy and especially in lepra-reaction. In the present study the authors have investigated the functional status of the kidneys of lepromatous leprosy patients by focussing attention to parameters like acidification of urine, glomerular filtration rate and excretion of a foreign dye administered intramuscularly. This study revealed a decreased ability to acidify urine and to excrete the dye as well as a drop in glomerular filtration rate in untreated LL patients. The said disturbances were more pronounced in lepra reaction.
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