02217nas a2200373   4500000000100000008004100001260001700042653001500059653001000074653000900084653001000093653002100103653001700124653001100141653002100152653002100173653001100194653002300205653001200228653000900240653001600249653001600265653003000281100001600311700001500327700001400342700001600356245010500372300001100477490000700488050003200495520130200527022001401829       1999                            d  c1999 Apr-Jun10aAdolescent10aAdult10aAged10aChild10aDisabled Persons10aFacial Bones10aFemale10aFoot Deformities10aHand Deformities10aHumans10aLeprostatic Agents10aleprosy10aMale10aMiddle Aged10aRadiography10aSeverity of Illness Index1 aChoudhuri H1 aThappa D M1 aKumar R H1 aElangovan S00aBone changes in leprosy patients with disabilities/deformities (a clinico-radiological correlation).  a203-150 v71  aInfolep Library - available3 a<p>One hundred and ten leprosy patients (96 males and 14 females, mean age 45.3 years) with disabilities/deformities were examined radiologically to evaluate bone changes and correlating them with clinical parameters. Most patients (98) had paucibacillary leprosy. The mean duration of leprosy was 7.4 years and that of deformity was 4.1 years. Ten patients presented with reaction. Seventy-five (68.2%) patients had received a full course of antileprosy treatment. The overall prevalence of bone changes was 87.3% (96 patients); specific, non-specific, osteoporotic and facial changes were seen in 44.5%, 75.5%, 38.2% and 9.1% of the patients respectively. Among the specific bone changes, primary periosteitis (28.2%) and "bone cysts" (22.7%) were the more common findings. Among the non-specific bone changes, terminal phalangeal absorption (48.2%), soft tissue changes (44.5%) and concentric absorption (32.7%) were more common. Specific bone changes showed a significant (P < 0.05) increase with lack of or incomplete antileprosy treatment. Non-specific bone changes showed significant correlation (P < 0.05) with increasing duration of disease, lack of or partial treatment and rising disability index. Osteoporotic changes showed a significant relationship with rising disability index.</p>  a0254-9395