01290nas a2200265 4500000000100000008004100001260001300042653002200055653001200077653001100089653002400100653001200124653000900136653001700145653001800162100001900180700001400199700001400213245010700227300001100334490000700345050003200352520062600384022001401010 1981 d c1981 Oct10aAction Potentials10aAnimals10aFemale10aIn Vitro Techniques10aleprosy10aMice10aNerve Fibers10aSciatic Nerve1 aVidyasagar P B1 aDamle P S1 aAntia N H00aA study of the sciatic nerve compound action potential in vitro in normal and M. leprae infected mice. a537-550 v53 aInfolep Library - available3 a

A study of the sciatic nerve compound action potential was carried out, in normal and non-immunosuppressed swiss mice (white) inoculated with 5000 M. leprae in each hind foot pad, from 1st to 7th post-inoculation month. In normal mice, the threshold for stimulation, maximum amplitude, duration and conduction velocity of all the three components of the compound action potential were measured. Progressive changes were noted in amplitude and the threshold for stimulations of the unmyelinated fibre ('C' fibres) potentials. These changes were compared with the changes observed in the myelinated fibre potentials.

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