01388nas a2200277   4500000000100000008004100001260001600042653002900058653001800087653001800105653001100123653001200134653001200146100001500158700001100173700001500184700001600199700001300215700001600228700001700244245006800261300001300329490000700342520074700349022001401096       1981                            d  c1981 Dec 1210aAntigen-Antibody Complex10aComplement C310aComplement C410aHumans10aleprosy10aSenegal1 aGeniteau M1 aAdam C1 aVerroust P1 aPasticier A1 aSaimot G1 aCoulaud J P1 aLanguillon J00a[Immune complexes and complement in leprosy (author's transl)].  a3697-7000 v103 a<p>The sera of 87 Senegalese patients with various forms of leprosy were investigated. Two of the most reliable methods were used to detect circulating immune complexes : the radiolabelled C1q binding test and the Raji cell binding technique. Several fractions of complement, including C3, C4, factor B and the C3d product of C3 were also assayed. A material having the properties of immune complexes was detected in lepromatous and reactional leprosy. In tuberculous leprosy, only the Raji cell binding technique gave positive results. C3 and C4 were normal or slightly raised, but C3d was increased in all forms of the disease. There was no significant correlation between C3d values and the results of immune complexes detection tests.</p>  a0301-1518