01156nas a2200241   4500000000100000008004100001260001300042653001200055653001200067653002200079653001100101653001200112653000900124653001300133100001600146700001600162245010000178300001100278490000700289050003200296520057200328022001400900       1980                            d  c1980 Jul10aAnimals10aDapsone10aFollow-Up Studies10aHumans10aleprosy10aMice10aRifampin1 aGirdhar B K1 aDesikan K V00aEffect of single dose (1500 mg) rifampicin on infectivity of patients with lepromatous leprosy.  a359-650 v52  aInfolep Library - available3 a<p>The effect of treatment with a single dose of Rifampicin (1500 mg) has been investigated in previously untreated lepromatous leprosy patients. A group of 14 cases were administered 1500 mg of Rifampicin in a single dose along with 100 mg Dapsone (DDS) daily. A control group received only 100 mg DDS daily. The patients were followed up for a period of 24 weeks. The clinical, bacteriological and results of mouse foot-pad inoculations do not indicate a significant advantage of the addition of a single dose of Rifampicin to the conventional therapy with DDA.</p>  a0024-1024