01671nas a2200337   4500000000100000008004100001260001300042653001500055653001000070653003000080653002600110653001100136653001600147653001100163653001200174653002000186653000900206653001600215653001400231653002600245653002600271653001800297100001300315700001900328245006000347856004100407300001000448490000700458520085400465022001401319       1980                            d  c1980 Sep10aAdolescent10aAdult10aCell Migration Inhibition10aChemotaxis, Leukocyte10aFemale10aGlucosamine10aHumans10aleprosy10aLeukocyte Count10aMale10aMiddle Aged10aMonocytes10aNitroblue Tetrazolium10aReceptors, Complement10aReceptors, Fc1 aMasuda A1 aScheinberg M A00aPeripheral blood monocyte function in leprosy patients.  uhttp://ila.ilsl.br/pdfs/v48n3a02.pdf  a254-90 v483 a<p>The activities of monocytes from lepromatous (LL) and tuberculoid (TT) leprosy patients were studied in a variety of in vitro systems. In assays of receptor activity, increased densities of Fc and C3b receptor sites were observed in monocytes of LL and TT patients as compared to normals. No differences were observed between the polar forms of the disease. Similar results were obtained in the nitroblue tetrazolium (NBT) reduction test. Glucosamine incorporation by monocytes from LL and TT patients was not significantly different from that by monocytes from normal controls. A diminished monocyte spontaneous migration and chemotactic activity to lymphocyte derived chemotactic factor (LDCF) was found in both forms of the disease. Plasma inhibitory factor of monocyte chemotaxis was more evident in the lepromatous form of the disease.</p>
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