01144nas a2200217 4500000000100000008004100001260001300042653001700055653001100072653001200083653001400095100001400109700001700123700001500140245003900155856004100194300001000235490000700245520066000252022001400912 1980 d c1980 Dec10aHaptoglobins10aHumans10aleprosy10aPhenotype1 aSaoji A M1 aJariwala H J1 aKelkar S S00aHaptoglobin phenotypes in leprosy. uhttp://ila.ilsl.br/pdfs/v48n4a08.pdf a422-50 v483 a

Serum haptoglobin phenotypes were studied in 80 patients with leprosy classified according to the criteria of Ridley and Jopling. The distribution of phenotypes was: 2-2, 65%; 2-1, 27.5%; 1-1, 1.25%; and 0-0, 6.25%. This distribution was not significantly different from the controls except for the phenotype 0-0 (p less than 0.02). Thus, although this genetic marker did not correlate with the occurrence of the variety of disease, it is possible that leprosy caused inhibition of haptoglobin synthesis and therefore an apparent increased frequency of the 0-0 phenotype. Evidence for such a secondary anhaptoglobinemia was available in one case.

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