01434nas a2200253   4500000000100000008004100001260001300042653001600055653002100071653001100092653001200103653002600115653000900141100001500150700001300165700001500178700001600193245007700209856004100286300001000327490000700337520082200344022001401166       1981                            d  c1981 Mar10aBCG Vaccine10aChild, Preschool10aHumans10aleprosy10aLymphocyte Activation10aMale1 aStoner G L1 aBelehu A1 aNsibambi J1 aWarndorff J00aBorderline tuberculoid leprosy following BCG vaccination. A case report.  uhttp://ila.ilsl.br/pdfs/v49n1a03.pdf  a16-200 v493 a<p>Borderline tuberculoid leprosy was diagnosed clinically and histologically in a four year-old boy about 6 months after intradermal vaccination with BCG. His mother reported that a lesion began to appear above the vaccination site on the arm 2 weeks after the vaccination, and a second lesion appeared on the chin 2 months later. Responses in the lymphocyte transformation test to sonicated Mycobacterium leprae, BCG, and to PPD were consistent with a tuberculoid leprosy infection. Precipitation of BT leprosy by intradermal BCG infection may possibly represent the overcoming of a phase of primary suppression in an individual who might otherwise have progressed toward lepromatous leprosy. The implications of this hypothesis for the planning of a controlled trial of an anti-leprosy vaccine are discussed.</p>
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