01588nas a2200301   4500000000100000008004100001260001300042653001500055653001000070653001000080653003200090653001100122653001100133653001200144653000900156653001600165100001400181700001500195700001600210700001600226700001700242245012900259856004100388300000900429490000700438520082700445022001401272       1981                            d  c1981 Mar10aAdolescent10aAdult10aChild10aEvaluation Studies as Topic10aFemale10aHumans10aleprosy10aMale10aMiddle Aged1 aREICH C V1 aGuinto R S1 aCellona R V1 aFajardo T T1 aMadarang M G00aEvaluation of a new blood test for its potential to indicate leprosy infection prior to the appearance of clinical symptoms.  uhttp://ila.ilsl.br/pdfs/v49n1a04.pdf  a21-60 v493 a<p>A test is described that utilized a laser nephelometric measure of the interaction between human serum and a leprosy biopsy suspension to demonstrate household contact with a leprosy index case. None of the test sera was from persons with clinical evidence of the disease. There was a 5:1 ratio of higher level reactors in sera from household contacts vs high level reactors in sera from persons in the surrounding community. This did not appear to be a result of age, sex, family relationship to the index case, or clinical character of the index case. Some index cases had high level serum reactors among their contacts; others did not. This phenomenon was not a function of the clinical classification of the index case. The reason is unknown. This test should provide another practical means to study leprosy.</p>
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