01607nas a2200349   4500000000100000008004100001260001300042653001500055653001000070653000900080653001200089653001100101653001200112653001700124653000900141653001600150653001300166653002500179653001100204100001200215700001200227700001100239700001300250700001300263700001400276245006900290300001000359490000700369050003200376520083500408022001401243       1982                            d  c1982 Jan10aAdolescent10aAdult10aAged10aAtrophy10aHumans10aleprosy10aLeydig Cells10aMale10aMiddle Aged10aOrchitis10aSeminiferous Tubules10aTestis1 aKumar B1 aRaina A1 aKaur S1 aDash R J1 aSamuel E1 aDatta B N00aClinico-pathological study of testicular involvement in leprosy.  a48-550 v54  aInfolep Library - available3 a<p>Twenty five patients of lepromatous leprosy were studied clinically and histopathologically for testicular involvement. Testicular pain or swelling was the commonest complaint (68%) followed by sterility (28%) and impotence (4%). Reduced testicular size associated with soft feel was observed in 76% patients. Gynaecomastia was present in 36% and altered sexual hair pattern in 24%. Eleven out of sixteen (69%) patients had oligo/azoospermia. Out of the twenty testicular biopsies 15 (75%) had definite histological evidence of leprous pathology, irrespective of testicular size, semen picture and clinical signs and symptoms. One out of three epididymal biopsies showed minimal changes. Histopathological changes varied markedly, it was not possible to categorize these into vascular, interstitial and obliterative phases.</p>  a0024-1024