01683nas a2200349   4500000000100000008004100001260001300042653001500055653001000070653002500080653002500105653003200130653001000162653002000172653002000192653001100212653001100223653002900234653001200263653000900275653001600284100001500300700001500315700001500330700001800345245004900363300001000412490000700422050003200429520085800461022001401319       1982                            d  c1982 Jan10aAdolescent10aAdult10aAlanine Transaminase10aAlkaline Phosphatase10aAspartate Aminotransferases10aChild10aCholinesterases10aCreatine Kinase10aFemale10aHumans10aIsocitrate Dehydrogenase10aleprosy10aMale10aMiddle Aged1 aBulakh P M1 aKowale C N1 aRanade S M1 aDeshpande V A00aSerum enzyme profile in tuberculoid leprosy.  a69-740 v54  aInfolep Library - available3 a<p>Serum enzyme profile was studied in 74 patients with Tuberculoid leprosy and compared with that of 100 healthy controls. The enzymes studied were Aspartate and Alanine Transaminase, Isocitric dehydrogenase, Alkaline phosphatase Choline esterase and Creatine kinase. Both Transaminase and Alkaline phosphatase were in general within normal limits in Tuberculoid leprosy. Creatine kinase levels were found to be significantly elevated. In some of these cases raised levels of Serum Aspartate Transaminase was also noticed--evidence for skeletal muscle destruction. Mild increases in Isocitric dehydrogenase and a concomitant increase in Alanine Transaminase in some of the patients suggest a sub-clinical hepatic damage. A statistically significant decrease in Serum Choline esterase level was noticed in this study on Tuberculoid leprosy patients.</p>  a0024-1024