00884nas a2200217   4500000000100000008004100001260001300042653001200055653001100067653001200078653002600090653002400116100001500140700001900155245007600174300001000250490000700260050003200267520035300299022001400652       1982                            d  c1982 Apr10aDapsone10aHumans10aleprosy10aLymphocyte Activation10aPhytohemagglutinins1 aHardas U D1 aJalgaonkar S V00aPHA induced blastoid transformation of lymphocytes in leprosy contacts.  a270-40 v54  aInfolep Library - available3 a<p>PHA-induced blastoid transformation of lymphocytes was studied in 29 contacts of leprosy patients. 21 contacts taking DDS as prophylaxis showed significant depression of lymphocyte transformation while 8 contacts not taking DDS showed no depression as compared to controls. DDS thus has an inhibitory effect on cell mediated immune response.</p>  a0024-1024