01184nas a2200253 4500000000100000008004100001260001300042653002000055653001100075653001200086653001600098653001400114653002500128653001100153100001600164700001300180700002300193245005300216300001000269490000700279050003200286520059800318022001400916 1980 d c1980 Apr10aCells, Cultured10aHumans10aleprosy10aMacrophages10aMonocytes10aMycobacterium leprae10aSepsis1 aVeliath A J1 aBedi B M1 aBALASUBRAHMANYAN M00aMacrophage culture from untreated leprosy cases. a203-80 v52 aInfolep Library - available3 a

Macrophage cultures from the peripheral blood were performed in 25 untreated bacteraemic leprosy patients. The monocytes on conversion to macrophages in culture continued to harbour solidly stained M. Leprae till the termination of culture. It is suggested that the majority of these bacilli are viable and capable of multiplication intracellularly in macrophages if cultures could be maintained for sufficiently long periods. It was observed that bacteraemia in Leprosy can be detected by the culture technic. It has been found to be more sensitive than the leukocyte adherence method.

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